Search results for " Anti-aging strategies"

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Aging Successfully: The Role of Genetics and Environment in the Era of the Aging-Boom. Potential Therapeutic Implications

2019

Aging is one of the main health-related challenges in the world. The average life expectancy of the global population at birth is increasing up to 72 years, in 2016 and it increases about two years every decade. The healthcare costs in many countries are very high because of the increased number of unhealthy populations, and the consequent increase of severe age-related disabilities [1]. Therefore, the goal of the future should be the achievement of the so-called “health-span” (healthy-life-span), more than the treatment of age-related disease to prevent the collapse of the health system. In order to achieve this objective, it is necessary to identify new targets and biomarkers and to addre…

GerontologyAgingEye DiseasesLongevityMEDLINEAging Anti-aging strategies DNA methylation Immunesenescence TLR agonist Immunesenescence Melatonin MiRNA Neuroinflammation Vasculoprotection01 natural sciencesBoomEpigenesis Genetic03 medical and health sciencesDrug DiscoveryHumansMedicineMelatonin030304 developmental biologyEpigenesisSettore MED/04 - Patologia GeneralePharmacology0303 health sciencesbusiness.industryToll-Like ReceptorsVaccination0104 chemical sciencesMicroRNAs010404 medicinal & biomolecular chemistryMethotrexateImmune SystembusinessIntroductory Journal ArticleCurrent Pharmaceutical Design
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